Carbohydrates Biochemistry Set 5

/31

Biochemistry (Carbohydrates And Carbohydrate Metabolism Set 5)

MCQ

1 / 31

1. Cori cycle is

A) uptake of glycose

B) Both (A) & (B

C) reuse of glucose

D) Synthesis of glucose

2 / 31

2. How many ATPs are produced in the
conversion of phosphoenol pyruvate to
citrate

A) 2

B) 6

C) 4

D) 1

3 / 31

3. The reaction catalysed by phosphofructokinase

A) Is the rate-limiting reaction of the glycolytic pathway

B) Uses fruitose-1-phosphate as substrate

C) Is inhibited by fructose 2, 6-bisphosphate

D) Is activated by high concentrations of ATP and citrate

4 / 31

4. Out of 24 mols of ATP formed in TCA cycle,
2 molecules of ATP can be formed at
“substrate level” by which of the
following reaction

A) socitrate→ Oxaloacetate

B) Succinic acid→ Fumarate

C) Succinylcat→ Succinic acid

D) Citric acid→ Isocitric acid

5 / 31

5. An allosteric enzyme responsible for
controlling the rate of T.C.A cycle is

A) Isocitrate dehydrogenase

B) Aconitase

C) Malate dehydrogenase

D) Fumarase

6 / 31

6. For conversion of oxaloacetate to
phosphoenol pyruvate, high energy
molecule is required in the form of

A) ITP only

B) GTP (or) ITP

C) GTP only

D) None of these

7 / 31

7. Which one of the following would be
expected in pyruvate kinase deficiency

A) Increased phosphorylation of Glucose to Glucose-6-phosphate

B) Hemolytic anemia

C) Decreased ratio of ADP to ATP in R.B.C

D) Increased levels of lactate in the R.B.C

8 / 31

8. All of the following statements about the
enzymic complex that carries out the
synthesis of ATP during oxidative
phosphorylation are correct except

A) It is inhibited by oligomycin

B) It can exhibit ATPase activity

C) ) It can bind molecular O2

D) It is located on the matrix side of the inner mitochondrial membrane

9 / 31

9. Which of the following enzyme is not
involved in HMP shunt

A) Glucose-6-p-dehydrogenase

B) Glyceraldehyde-3-p dehydrogenase

C) Transketolase

D) Phosphogluconate dehydrogenase

10 / 31

10. The synthesis of glucose from pyruvate
by gluconeogenesis

A) Requires the participation of biotin

B) Requires oxidation/reduction of FAD

C) Occurs exclusively in the cytosol

D) Is inhibited by elevated level of insulin

11 / 31

11. Glucokinase

A) Is widely distributed in Prokaryotes

B) Has a high km for glucose and hence is important in the phosphorylation of glucose primarily after ingestion of a carbohydrate rich meal

C) Is widely distributed and occurs in most mammalian tissues

D) None of these

12 / 31

12. The conversion of pyruvate to acetyl CoA
and CO2

A) Involves the participation of lipoic acid

B) Depends on the coenzyme biotin

C) Occurs in the cytosol

D) Is reversible

13 / 31

13. The reaction catalysed by phosphofructokinase

A) Is inhibited by fructose 2, 6-bisphosphate

B) Uses fruitose-1-phosphate as substrate

C) Is activated by high concentrations of ATP and citrate

D) Is the rate-limiting reaction of the glycolytic pathway

14 / 31

14. Which one of the following statements
concerning glucose metabolism is correct

A) Pyruvate kinase catalyses an irreversible reaction

B) The conversion of Glucose to lactate occurs only in the R.B.C

C) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte

D) Glucose enters most cells by a mechanism in which Na+ and glucose are co-transported

15 / 31

15. The glycolysis is regulated by

A) All of these

B) Phosphofructokinase

C) Hexokinase

D) Pyruvate kinase

16 / 31

16. The free energy change, AG

A) Can only be calculated when the reactants and products are present at 1mol/1 concentrations

B) Is equal to –RT in keq

C) Is directly proportional to the standard free energy change, AG

D) Is equal to zero at equilibrium

17 / 31

17. Under standard conditions

A) The standard free energy change ∆G, is equal to 0

B) Keq is equal to 1

C) The free energy change, ∆G°, is equal to the standard free energy change, ∆G°

D) The free energy change ∆G°, is equal to 0

18 / 31

18. An uncoupler of oxidative phosphorylation such as dinitropheno

A) Inhibits electron transport without impairment of ATP synthesis

B) Inhibits electron transport and ATP synthesis

C) Allow electron transport to proceed without ATP synthesis

D) Specially inhibits cytochrome b

19 / 31

19. Electron transport and phosphorylation
can be uncoupled by compounds that
increase the permeability of the inner
mitochondrial membrane to

A) All of these

B) Uncouplers

C) Protons

D) Electrons

20 / 31

20. Compared to the resting state, vigorously
contracting muscle shows

A) An increased conversion of pyruvate to lactate

B) A decreased NADH/NAD+ ratio

C) Decreased concentration of AMP

D) Decreased oxidation of pyruvate of CO2 and water

21 / 31

21. Reduced glutathione functions in R.B.Cs
to

A) Reduce oxidizing agents such as H2O2

B) Produce NADPH

C) Produce NADH

D) Reduce methemoglobin to hemoglobin

22 / 31

22. Glycogen is present in all body tissues
except

A) Kidney

B) Stomach

C) Liver

D) Brain

23 / 31

23. How many ATP molecules will be required
for conversion of 2-molecules of Lactic acid
to Glucose

A) 4

B) 6

C) 2

D) 8

24 / 31

24. Which of the following reactions is unique
to gluconeogenesis

A) Lactate Pyruvate

B) Glucose-6-phosphate Fructose-6-phosphate

C) Oxaloacetate phosphoenol pyruvate

D) Phosphoenol pyruvate pyruvate

25 / 31

25. In presence of the following cofactor,
pyruvate carboxylase converts pyruvate
to oxaloacetate

A) Protein

B) CO2 and ATP

C) CO2

D) ATP, Protein and CO2

26 / 31

26. Which one of the following compounds
cannot give rise to the net synthesis of
Glucose

A) α-ketoglutarate

B) Acetyl CoA

C) Lactate

D) Glycerol

27 / 31

27. The more positive the E0, the greater the
tendency of the oxidant member of that
pair to

A) Lose and gain electrons

B) Lose (or) gain electrons

C) Gain electrons

D) Lose electrons

28 / 31

28. Reduced glutathione functions in R.B.Cs
to

A) Produce NADPH

B) Reduce oxidizing agents such as H2O2

C) Reduce methemoglobin to hemoglobin

D) Produce NADH

29 / 31

29. Which of the following statements
regarding T.C.A cycle is true

A) It is an anaerobic process

B) It contains no intermediates for GluconeogenesisIt contains no intermediates for Gluconeogenesis

C) It is amphibolic in nature

D) It occurs in cytosol

30 / 31

30. Phenylalanine is the precursor of

A) Histamine

B) L-DOPA

C) Tyrosine

D) Throxine

31 / 31

31. Phenylalanine is the precursor of

A) Throxine

B) L-DOPA

C) Histamine

D) Tyrosine

Your score is

The average score is 41%

Carbohydrates Biochemistry Set 5

Follow Us on Social Media