Proteins And Protein Metabolism Set 4

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Biochemistry (Proteins And Protein Metabolism Set 4)

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1. The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is

A) Loss of feed back inhibition of HMG reductase

B) Loss of apolipoprotein B

C) Increased production of LDL from VLDL

D) Functional deficiency of plasma membrane receptors for LDL

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2. All active prostaglandins have at least one
double bond between positions

A) 7 and 8

B) 10 and 11

C) 13 and 14

D) 16 and 17

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3. A lipoprotein inversely related to the
incidence of coronary artherosclerosis is

A) VLDL

B) IDL

C) LDL

D) HDL

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4. The optimal pH for the enzyme chymotrypsin is

A) 2.0

B) 4.0

C) 6.0

D) 8.0

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5. HDL2 have the density in the range of

A) 1.006–1.019

B) 1.019–1.032

C) 1.032–1.063

D) 1.063–1.125

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6. Familial hypertriaacylglycerolemia is
associated with

A) Over production of VLDL

B) Increased LDL concentration

C) Increased HDL concentration

D) Slow clearance of chylomicrons

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7. Trypsinogen is converted to active trypsin by

A) Enterokinase

B) Bile salts

C) HCl

D) Mg++

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8. Chymotrypsin is specific for peptide bonds containing

A) Uncharged amino acid residues

B) Acidic amino acids

C) Basic amino acid

D) Small amino acid residues

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9. For synthesis of prostaglandins, the
essential fatty acids give rise to a fatty
acid containing

A) 12 carbon atoms

B) 16 carbon atoms

C) 20 carbon atoms

D) 24 carbon atoms

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10. Pepsin acts on denatured proteins to produce

A) Proteoses and peptones

B) Polypeptides

C) Peptides

D) Dipeptides

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11. β-lipoproteins have the density in the
range of

A) 0.95–1.006

B) 1.006–1.019

C) 1.019–1.063

D) 1.063–1.125

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12. Normal range of plasma total phospholipids is

A) 0.2–0.6 mmol/L

B) 0.9–2.0 mmol/L

C) 1.8–5.8 mmol/L

D) 2.8–5.3 mmol/L

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13. IDL have the density in the range of

A) 0.95–1.006

B) 1.006–1.019

C) 1.019–1.032

D) 1.032–1.163

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14. An expopeptidase is

A) Trypsin

B) Chymotrypsin

C) Elastase

D) Elastase

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15. In abetalipoproteinemia, the biochemical
defect is in

A) Apo-B synthesis

B) Lipprotein lipase activity

C) Cholesterol ester hydrolase

D) LCAT activity

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16. Aspirin inhibits the activity of the enzyme:

A) Lipoxygenase

B) Cyclooxygenase

C) Phospholipae A1

D) Phospholipase A2

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17. The enzyme trypsin is specific for peptide bonds of

A) Basic amino acids

B) Acidic amino acids

C) Aromatic amino acids

D) Next to small amino acid residues

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18. The optimal pH for the enzyme rennin is

A) 2.0

B) 4.0

C) 8.0

D) 6.0

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19. In adipose tissue prostaglandins decrease

A) Lipogenesis

B) Lipolysis

C) Gluconeogenesis

D) Gluconeogenesis

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20. A lipoprotein associated with high
incidence of coronary atherosclerosis is

A) LDL

B) VLDL

C) IDL

D) HDL

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21. Pepsinogen is converted to active pepsin by

A) HCl

B) Bile salt

C) Ca++

D) Enterokinase

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22. The optimal pH for the enzyme pepsin is

A) 1.0–2.0

B) 4.0–5.0

C) 5.2–6.0

D) 5.8–6.2

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23. The optimal pH for the enzyme trypsin is

A) 1.0–2.0

B) 2.0–4.0

C) 5.2–6.2

D) 5.8–6.2

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24. Renin converts casein to paracasein in presence of

A) Ca++

B) Mg++

C) Na+

D) K+

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25. A ’suicide enzyme’ is

A) Cycloxygenase

B) Lipooxygenase

C) Phospholipase A1

D) Phospholipase A2

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Proteins And Protein Metabolism Set 4

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