Enzymes Questions Set 1

1. From the L ineweaver-Burk p lot of Michaelis-Menten equation, Km and Vmax can be determined

when V is the reaction velocity at substrate concentration S,the X-axis experimental data are expressed as

2. Activation or inactivation of certain key regulatory enzymes is accomplished by
covalent modification of the amino acid:

3. A sigmoidal plot of substrate concentration ([S]) verses reaction velocity (V) may
indicate

4. A demonstrable inducer is absent in

5. Fabry’s disease is due to the deficiency of
the enzyme:

6. The kinetic effect of purely competitive
inhibitor of an enzyme

7. Farber’s disease is due to the deficiency
of the enzyme:

8. An example of lyases is

9. The compound which has the lowest density is

10. Krabbe’s disease is due to the deficiency
of the enzyme:

11. An example of ligases is

12. Enzymes, which are produced in inactive
form in the living cells, are called

13. The enzyme which can add water to a carbon-carbon double bond or remove
water to create a double bond without breaking the bond is

14. Neimann-Pick disease is due to the deficiency of the enzyme:

15. An inducer is absent in the type of enzyme:

16. Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the
activity of the enzyme:

17. From arachidonate, synthesis of prostaglandins is catalysed by

18. The Km of the enzyme giving the kinetic
data as below is

19. In reversible non-competitive enzyme
activity inhibition

20. A synthetic nucleotide analogue, used in organ transplantation as a suppressor of
immunologic rejection of grafts is

21. Fischer’s ‘lock and key’ model of the enzyme action implies that

22. In reversible non-competitive enzyme
activity inhibition

23. Gaucher’s disease is due to the deficiency
of the enzyme:

24. A Holoenzyme is

25. Example of an extracellular enzyme is