Proteins And Protein Metabolism Set 3

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Biochemistry (Proteins And Protein Metabolism Set 3)

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1. The apolipoprotein which acts as activator
of LCAT is

A) A-I

B) A-IV

C) C-II

D) D

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2. Ceruloplasmin is

A) α1-globulin

B) α2-globulin

C) β-globulin

D) None of these

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3. Distance traveled per turn of α−helix in
nm is

A) 0.53

B) 0.54

C) 0.44

D) 0.48

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4. Fibrous proteins have axial ratio

A) Less than 10

B) Less than 10 and generally not greater than 3–4

C) Generally 10

D) Greater than 10

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5. In proteins the α-helix and β-pleated sheet
are examples of

A) Primary structure

B) Secondary structure

C) Tertiary structure

D) Quaternary structure

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6. Tertiary structure of a protein describes

A) The order of amino acids

B) Location of disulphide bonds

C) Loop regions of proteins

D) The ways of protein folding

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7. The apolipoprotein which acts as ligand
for LDL receptor is

A) B-48

B) B-100

C) A

D) C

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8. Both α-helix and β-pleated sheet conformation of proteins were proposed by

A) Watson and Crick

B) Pauling and Corey

C) Waugh and King

D) Y.S.Rao

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9. Along the α-helix each amino acid residue
advances in nm by

A) 0.15

B) 0.10

C) 0.12

D) 0.12

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10. Serum LDL has been found to be increased
in

A) Obstructive jaundice

B) Hepatic jaundice

C) Hemolytic jaundice

D) Malabsorption syndrome

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11. The apolipoprotein which forms the
integral component of chylomicron is

A) B-100

B) B-48

C) C

D) D

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12. The a-helix of proteins is

A) A pleated structure

B) Made periodic by disulphide bridges

C) A non-periodic structure

D) Stabilised by hydrogen bonds between NH and CO groups of the main chain

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13. The lipoprotein with the fastest electrophoretic mobility and the lowest triglyceride content is

A) Chylomicron

B) VLDL

C) IDL

D) HDL

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14. Each turn of α-helix contains the amino
acid residues (number):

A) 3.6

B) 3.0

C) 4.2

D) 4.5

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15. The hydrogen bonds between peptide
linkages of a protein molecules are interfered by

A) Guanidine

B) Uric acid

C) Oxalic acid

D) Salicylic acid

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16. Globular proteins have completely folded,
coiled polypeptide chain and the axial
ratio (ratio of length to breadth) is

A) Less than 10 and generally not greater than 3–4

B) Generally 10

C) Greater than 10 and generally 20

D) Greater than 10Greater than 10

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17. The apolipoprotein which acts as activator
of extrahepatic lipoprotein is

A) Apo-A

B) Apo-B

C) Apo-C

D) Apo-D

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18. The lipoprotein associated with activation
of LCAT is

A) HDL

B) LDL

C) VLDL

D) IDL

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19. The primary structure of fibroin, the
principal protein of silk worm fibres
consists almost entirely of

A) Glycine

B) Aspartate

C) Keratin

D) Tryptophan

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20. In a protein molecule the disulphide bond
is not broken by

A) Reduction

B) Oxidation

C) Denaturation

D) X-ray diffraction

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21. the number of helices present in a
collagen molecule is

A) 1

B) 2

C) 3

D) 4

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22. Denaturation of proteins results in

A) Disruption of primary structure

B) Breakdown of peptide bonds

C) Destruction of hydrogen bonds

D) Irreversible changes in the molecule

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23. The technique for purification of proteins
that can be made specific for a given
protein is

A) Gel filtration chromotography

B) Ion exchange chromatography

C) Electrophoresis

D) Affinity chromatography

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24. At the lowest energy level α-helix of
polypeptide chain is stabilised

A) By hydrogen bonds formed between the H of peptide N and the carbonyl O of the residue

B) Disulphide bonds

C) Non polar bonds

D) Ester bonds

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25. The apolipoprotein which from the
integral component of VLDL is

A) B-100

B) B-48

C) A

D) D

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Proteins And Protein Metabolism Set 3

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