Enzymes Questions Set 1

1. The enzyme which can add water to a carbon-carbon double bond or remove
water to create a double bond without breaking the bond is

2. A Holoenzyme is

3. Activation or inactivation of certain key regulatory enzymes is accomplished by
covalent modification of the amino acid:

4. An example of lyases is

5. Neimann-Pick disease is due to the deficiency of the enzyme:

6. Example of an extracellular enzyme is

7. Farber’s disease is due to the deficiency
of the enzyme:

8. A demonstrable inducer is absent in

9. A sigmoidal plot of substrate concentration ([S]) verses reaction velocity (V) may
indicate

10. The compound which has the lowest density is

11. A synthetic nucleotide analogue, used in organ transplantation as a suppressor of
immunologic rejection of grafts is

12. In reversible non-competitive enzyme
activity inhibition

13. Enzymes, which are produced in inactive
form in the living cells, are called

14. Fischer’s ‘lock and key’ model of the enzyme action implies that

15. From the L ineweaver-Burk p lot of Michaelis-Menten equation, Km and Vmax can be determined

when V is the reaction velocity at substrate concentration S,the X-axis experimental data are expressed as

16. From arachidonate, synthesis of prostaglandins is catalysed by

17. An example of ligases is

18. An inducer is absent in the type of enzyme:

19. Gaucher’s disease is due to the deficiency
of the enzyme:

20. Krabbe’s disease is due to the deficiency
of the enzyme:

21. In reversible non-competitive enzyme
activity inhibition

22. Fabry’s disease is due to the deficiency of
the enzyme:

23. Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the
activity of the enzyme:

24. The Km of the enzyme giving the kinetic
data as below is

25. The kinetic effect of purely competitive
inhibitor of an enzyme