Enzymes Questions Set 1

1. A synthetic nucleotide analogue, used in organ transplantation as a suppressor of
immunologic rejection of grafts is

2. Gaucher’s disease is due to the deficiency
of the enzyme:

3. Neimann-Pick disease is due to the deficiency of the enzyme:

4. An inducer is absent in the type of enzyme:

5. In reversible non-competitive enzyme
activity inhibition

6. A sigmoidal plot of substrate concentration ([S]) verses reaction velocity (V) may
indicate

7. Fabry’s disease is due to the deficiency of
the enzyme:

8. An example of lyases is

9. From arachidonate, synthesis of prostaglandins is catalysed by

10. From the L ineweaver-Burk p lot of Michaelis-Menten equation, Km and Vmax can be determined

when V is the reaction velocity at substrate concentration S,the X-axis experimental data are expressed as

11. The Km of the enzyme giving the kinetic
data as below is

12. Enzymes, which are produced in inactive
form in the living cells, are called

13. The kinetic effect of purely competitive
inhibitor of an enzyme

14. Farber’s disease is due to the deficiency
of the enzyme:

15. Activation or inactivation of certain key regulatory enzymes is accomplished by
covalent modification of the amino acid:

16. A Holoenzyme is

17. In reversible non-competitive enzyme
activity inhibition

18. The enzyme which can add water to a carbon-carbon double bond or remove
water to create a double bond without breaking the bond is

19. Krabbe’s disease is due to the deficiency
of the enzyme:

20. Example of an extracellular enzyme is

21. A demonstrable inducer is absent in

22. An example of ligases is

23. The compound which has the lowest density is

24. Fischer’s ‘lock and key’ model of the enzyme action implies that

25. Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the
activity of the enzyme: