Enzymes Questions Set 1

1. Farber’s disease is due to the deficiency
of the enzyme:

2. Gaucher’s disease is due to the deficiency
of the enzyme:

3. A synthetic nucleotide analogue, used in organ transplantation as a suppressor of
immunologic rejection of grafts is

4. An example of ligases is

5. The enzyme which can add water to a carbon-carbon double bond or remove
water to create a double bond without breaking the bond is

6. From the L ineweaver-Burk p lot of Michaelis-Menten equation, Km and Vmax can be determined

when V is the reaction velocity at substrate concentration S,the X-axis experimental data are expressed as

7. A demonstrable inducer is absent in

8. In reversible non-competitive enzyme
activity inhibition

9. Fabry’s disease is due to the deficiency of
the enzyme:

10. In reversible non-competitive enzyme
activity inhibition

11. A sigmoidal plot of substrate concentration ([S]) verses reaction velocity (V) may
indicate

12. An example of lyases is

13. A Holoenzyme is

14. Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the
activity of the enzyme:

15. Example of an extracellular enzyme is

16. From arachidonate, synthesis of prostaglandins is catalysed by

17. An inducer is absent in the type of enzyme:

18. Enzymes, which are produced in inactive
form in the living cells, are called

19. Neimann-Pick disease is due to the deficiency of the enzyme:

20. Krabbe’s disease is due to the deficiency
of the enzyme:

21. The Km of the enzyme giving the kinetic
data as below is

22. Activation or inactivation of certain key regulatory enzymes is accomplished by
covalent modification of the amino acid:

23. Fischer’s ‘lock and key’ model of the enzyme action implies that

24. The kinetic effect of purely competitive
inhibitor of an enzyme

25. The compound which has the lowest density is