Enzymes Questions Set 1

1. A sigmoidal plot of substrate concentration ([S]) verses reaction velocity (V) may
indicate

2. An inducer is absent in the type of enzyme:

3. Activation or inactivation of certain key regulatory enzymes is accomplished by
covalent modification of the amino acid:

4. In reversible non-competitive enzyme
activity inhibition

5. Gaucher’s disease is due to the deficiency
of the enzyme:

6. A Holoenzyme is

7. Krabbe’s disease is due to the deficiency
of the enzyme:

8. In reversible non-competitive enzyme
activity inhibition

9. Example of an extracellular enzyme is

10. Neimann-Pick disease is due to the deficiency of the enzyme:

11. Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the
activity of the enzyme:

12. The kinetic effect of purely competitive
inhibitor of an enzyme

13. The Km of the enzyme giving the kinetic
data as below is

14. A demonstrable inducer is absent in

15. The compound which has the lowest density is

16. An example of lyases is

17. An example of ligases is

18. The enzyme which can add water to a carbon-carbon double bond or remove
water to create a double bond without breaking the bond is

19. From arachidonate, synthesis of prostaglandins is catalysed by

20. From the L ineweaver-Burk p lot of Michaelis-Menten equation, Km and Vmax can be determined

when V is the reaction velocity at substrate concentration S,the X-axis experimental data are expressed as

21. A synthetic nucleotide analogue, used in organ transplantation as a suppressor of
immunologic rejection of grafts is

22. Fabry’s disease is due to the deficiency of
the enzyme:

23. Farber’s disease is due to the deficiency
of the enzyme:

24. Enzymes, which are produced in inactive
form in the living cells, are called

25. Fischer’s ‘lock and key’ model of the enzyme action implies that