Enzymes Questions Set 1

1. A sigmoidal plot of substrate concentration ([S]) verses reaction velocity (V) may
indicate

2. In reversible non-competitive enzyme
activity inhibition

3. The kinetic effect of purely competitive
inhibitor of an enzyme

4. Krabbe’s disease is due to the deficiency
of the enzyme:

5. In reversible non-competitive enzyme
activity inhibition

6. The compound which has the lowest density is

7. Gaucher’s disease is due to the deficiency
of the enzyme:

8. From arachidonate, synthesis of prostaglandins is catalysed by

9. A demonstrable inducer is absent in

10. Neimann-Pick disease is due to the deficiency of the enzyme:

11. An example of lyases is

12. Fischer’s ‘lock and key’ model of the enzyme action implies that

13. From the L ineweaver-Burk p lot of Michaelis-Menten equation, Km and Vmax can be determined

when V is the reaction velocity at substrate concentration S,the X-axis experimental data are expressed as

14. Enzymes, which are produced in inactive
form in the living cells, are called

15. An example of ligases is

16. The Km of the enzyme giving the kinetic
data as below is

17. An inducer is absent in the type of enzyme:

18. Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the
activity of the enzyme:

19. Activation or inactivation of certain key regulatory enzymes is accomplished by
covalent modification of the amino acid:

20. A Holoenzyme is

21. Fabry’s disease is due to the deficiency of
the enzyme:

22. A synthetic nucleotide analogue, used in organ transplantation as a suppressor of
immunologic rejection of grafts is

23. Farber’s disease is due to the deficiency
of the enzyme:

24. The enzyme which can add water to a carbon-carbon double bond or remove
water to create a double bond without breaking the bond is

25. Example of an extracellular enzyme is