Fats And Fatty Acid Metabolism Set 2

/25

Biochemistry (Fats And Fatty Acid Metabolism Set 2)

1 / 25

1. Absence of phenylalanine hydroxylase
causes

A) Neonatal tyrosinemia

B) Phenylketonuria

C) Primary hyperoxaluria

D) Albinism

2 / 25

2. Neonatal tyrosinemia improves on administration of

A) Thiamin

B) Riboflavin

C) Pyridoxine

D) Ascorbic acid

3 / 25

3. Free fatty acids are transported in the blood

A) Combined with albumin

B) Combined with fatty acid binding protein

C) Combined with β -lipoprotein

D) In unbound free salts

4 / 25

4. Characteristic finding in Gaucher's disease is

A) Night blindness

B) Renal failure

C) Hepatosplenomegaly

D) Deafness

5 / 25

5. Fucosidosis is characterized by

A) Muscle spasticity

B) Liver enlargement

C) Skin rash

D) Kidney failure

6 / 25

6. The enzyme acyl-CoA synthase catalyses the conversion of a fatty acid of an active
fatty acid in the presence of

A) AMP

B) ADP

C) ATP

D) GTP

7 / 25

7. Long chain fatty acids are first activated
to acetyl-CoA in

A) Cytosol

B) Microsomes

C) Nucleus

D) Mitochondria

8 / 25

8. An important feature of Zellweger ’s
syndrome is

A) Hypoglycemia

B) Accumulation of phytanic acid in tissues

C) Skin eruptions

D) Accumulation of C26-C38 polyenoic acid in brain tissues

9 / 25

9. Plasma tyrosine level in Richner-Hanhart
syndrome is

A) 1–2 mg/dL

B) 2–3 mg/dL

C) 4–5 mg/dL

D) 8–10 mg/dL

10 / 25

10. Amount of phenylacetic acid excreted in
the urine in phenylketonuria is

A) 100–200 mg/dL

B) 200–280 mg/dL

C) 290–550 mg/dL

D) 600–750 mg/dL

11 / 25

11. Metachromatic leukodystrophy is due to
deficiency of enzyme:

A) α-Fucosidase

B) Arylsulphatase A

C) Ceramidase

D) Hexosaminidase A

12 / 25

12. The enzymes of β-oxidation are found in

A) Mitochondria

B) Cytosol

C) Golgi apparatus

D) Nucleus

13 / 25

13. Salkowski test is performed to detect

A) Glycerol

B) Cholesterol

C) Fatty acids

D) Vitamin D

14 / 25

14. Dietary fats after absorption appear in the circulation as

A) HDL

B) VLDL

C) LDL

D) Chylomicron

15 / 25

15. The cholesterol molecule is

A) Benzene derivative

B) Quinoline derivative

C) Steroid

D) Straight chain acid

16 / 25

16. A significant feature of Tangier disease is

A) Impairment of chylomicron formation

B) Hypotriacylglycerolmia

C) Absence of Apo-C-II

D) Absence of Apo-C-I

17 / 25

17. Long chain fatty acids penetrate the inner mitochondrial membrane

A) Freely

B) As acyl-CoA derivative

C) As carnitine derivative

D) Requiring Na dependent carrier

18 / 25

18. Richner-Hanhart syndrome is due to
defect in

A) Tyrosinase

B) Phenylalanine hydroxylase

C) Hepatic tyrosine transaminase

D) Fumarylacetoacetate hydrolase

19 / 25

19. An important finding of Fabry’s disease
is

A) Skin rash

B) Exophthalmos

C) Hemolytic anemia

D) Mental retardation

20 / 25

20. Gaucher’s disease is due to deficiency of
the enzyme:

A) Sphingomyelinase

B) Glucocerebrosidase

C) Galactocerbrosidase

D) β-Galactosidase

21 / 25

21. An important finding in Neimann-Pick
disease is

A) Leukopenia

B) Cardiac enlargement

C) Corneal opacity

D) Hepatosplenomegaly

22 / 25

22. Palmitic, oleic or stearic acid ester of cholesterol used in manufacture of cosmetic creams is

A) Elaidic oil

B) Lanoline

C) Spermaceti

D) Chaulmoogric oil

23 / 25

23. A significant feature of Broad Beta disease
is

A) Hypocholesterolemia

B) Hypotriacylglycerolemia

C) Absence of Apo-D

D) Abnormality of Apo-E

24 / 25

24. Molecular formula of cholesterol is

A) C27H45OH

B) C29H47OH

C) C29H47OH

D) C23H41OH

25 / 25

25. Carnitine is synthesized from

A) Lysine and methionine

B) Glycine and arginine

C) Aspartate and glutamate

D) Proline and hydroxyproline

Your score is

The average score is 40%

Fats And Fatty Acid Metabolism Set 2

Follow Us on Social Media