Hormones Questions Set 1

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Biochemistry (Hormones Set 1)

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1. Growth hormone causes hyperglycemia. It is a result of :

A) Decreased peripheral utilization of glucose

B) Decreased hepatic production via gluconeogenes

C) Increased glycolysis in muscle

D) Decrersed lipolysis

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2. The number of amino acids in human growth hormone is :

A) 91

B) 151

C) 191

D) 291

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3. ACTH stimulates the secretion of :

A) Glucocorticoids

B) Epinephrine

C) Thyroxine

D) Luteinizing hormone

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4. Hyperglycemic effect of glucocorticoids is due to :

A) Inactivation of protein phosphatase

B) Inactivation of fructose 1,6-biphosphatase

C) Stimulation of synthesis of pyruvate carboxylase

D) Stimulation of synthesis of eltroxykinase

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5. A specific cortisol binding protein, transcortin is a :

A) Albumin

B) α1-Globulin

C) α2-Globulin

D) β-Globulin

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6. A hormone secreted from posterior pituitary is :

A) Vasopressin

B) Thyrotropic hormone

C) Prolactin

D) Adrenocorticotropic hormone

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7. ACTH induces rise in :

A) Cyclic AMP

B) Cyclic GMP

C) Calcium

D) Magnesium

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8. Growth hormone is released by :

A) Somatostatin

B) Growth hormone releasing hormone

C) Prolactin release inhibiting hormone

D) Luteinizing releasing hormone

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9. The predominant glucocorticoid is :

A) Cortisol

B) Aldosterone

C) Dehydroephiandrosterone

D) Androstenedione

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10. Aldosterone synthesis occurs in :

A) Zona reticularis

B) Zona fasciculata

C) Zona glomerulosa

D) Chromaffian cells

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11. Excessive secretion of ACTH causes :

A) Cushing’s syndrome

B) Addison’s disease

C) Myxoedema

D) Thyrotoxicosis

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12. Biological activity of ACTH requires :

A) 10-N-terminal amino acid

B) 24-N-terminal amino acid

C) 24-C-terminal amino acid

D) 15-C-terminal amino acid

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13. The number of amino acids in prolactin is :

A) 134

B) 146

C) 172

D) 199

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14. A hormone secreted from anterior pituitary is :

A) Growth hormone

B) Vasopressin

C) Oxytocin

D) Epinephrine

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15. In adrenal gland the cholesterol is stored :

A) Mostly in the free form

B) Mostly in esterified form

C) Large amount of free form and less amount of esterified form

D) Equal amounts of free and esterified form

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16. All mammalian steroid hormones are formed from :

A) Purine

B) Pyrimidine

C) Cholesterol

D) Pyrrole

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17. Hormones :

A) Act as coenzyme

B) Act as enzyme

C) Influence synthesis of enzymes

D) Belong to B-complex group

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18. Adrenocorticotropic hormone (ACTH) is a
single polypeptide containing :

A) 25 amino acid

B) 39 amino acid

C) 49 amino acid

D) 52 amino acid

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19. Cortisol is synthesized in :

A) Zona fasiculata

B) Zona glomerulosa

C) Zona reticularis

D) Chromaffin cells

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20. Acromegaly results due to excessive release of :

A) Thyroxine

B) Growth hormone

C) Insulin

D) Glucagon

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21. The circulating concentration of ACTH in plasma is :

A) 0.05 mµ/100 m

B) 0.1–2.0 mµ/100 ml

C) 2.5–3.5 mµ/100 ml

D) 3.0–5.0 mµ/100 ml

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22. Cushing’s syndrome-a tumour associated disease of adrenal cortex, there is :

A) Decreased epinephrine production

B) Excessive cortisol production

C) Excessive epinephrine production

D) Decreased cortsoil production

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23. Hormone that bind to cell surface receptor
and require the second messenger camp is :

A) Antidiuretic hormone

B) Cholecystokinin

C) Calcitriol

D) Gastrin

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24. Hormone that binds to intracellular receptor is :

A) Adrenocorticotropic hormone

B) Thyroxine

C) Follicle stimulating hormone

D) Glucagon

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25. A very efficient inhibitor of steroid biosynthesis is :

A) Aminoglutethimide

B) Aminoimidazole

C) Aminoimidazolesuccinyl carboxamine

D) Aminopterin

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Hormones Questions Set 1

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