Saturn Medic
Embryology (Male Reproductive System)
MCQ
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The most common cause of female pseudointersexuality is
Female pseudo-intersex individuals have a 46, XX genotype. This condition is most commonly caused by congenital adrenal hyperplasia, in which the fetus produces excessive amounts of androgens. The high androgen level will masculinize the female genitalia
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The most common cause of male pseudointersexuality is
Male pseudo-intersex individuals have a 46, XY genotype. This condition is most commonly caused by inadequate production of testosterone and MIF by the fetal testes. The low testosterone and MIF levels will stunt the development of the male genitalia.
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The most common cause of testicular feminization syndrome is
The most common cause of testicular feminization syndrome is the lack of androgen receptors in the urogenital folds and labioscrotal swellings. Because these tissues lack androgen receptors, they are blind or unresponsive to androgens. Consequently, these tissues develop into female external genitalia even though the fetus has a 46, XY genotype.
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. A 17-year-old girl presents with a complaint of amenorrhea. Physical examination reveals good breast development and normal amount of pubic hair. A rudimentary vagina and a mobile mass within both the right and left labia majora are found on pelvic examination. Ultrasound reveals the absence of a uterus. What is the diagnosis?
This is a classic case of testicular feminization syndrome. A karyotype analysis would reveal that this normal-appearing 17-year-old girl actually has a 46, XY genotype. The mobile masses within the right and left labia majora are the testes and should be surgically removed because this tissue has a propensity toward malignant tumor formation. The most common cause of this syndrome is a lack of androgen receptors in the phallus, urogenital folds, and labioscrotal swellings.
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One day a 9-year-old girl surprisingly announces to her mother, “Guess what, mommy, I’m not a girl; I’m a boy.” The mother is shocked but does act on the comment. During the next few years, the mother notices some tomboyish behavior and difficulty in social adjustment at school. When the girl is 12 years old, puberty starts with a striking virilization of the external genitalia. The mother is extremely concerned and seeks medical attention. What is the most likely cause?
Reduced levels of androgens during fetal development of an XY male fetus cause a feminization of the male external genitalia such that the baby can be phenotypically mistaken for female. Parents raise the XY male baby as a girl until puberty or other medical problems bring the child to medical attention.
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Bilateral cryptorchidism usually results in
Sterility is a common result of bilateral cryptorchidism. When both testes fail to descend into the scrotum, the increased temperature to which they are exposed in the abdominal cavity will inhibit spermatogenesis.
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In the male, failure of the urethral folds to fuse completely results in
Failure of the urethral folds to fuse completely results in the external urethral orifice opening onto the ventral surface of the penis, a condition known as hypospadias.
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The Y chromosome carries a gene on its short arm that codes for
The gene product that is coded on the short arm of the Y chromosome is called the TDF
Your score is
The average score is 75%
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