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Connective Tissue — General Histology & Microscopy

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Connective Tissue
General Histology & Microscopy · Connective Tissue · medium
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Connective Tissue MCQs: practice questions

Sample Connective Tissue multiple-choice questions from General Histology & Microscopy.

  1. A biopsy shows large cells with one dominant lipid droplet displacing the nucleus to the periphery. Which cell is present?

    • A. Multilocular adipocyte
    • B. Mast cell
    • C. Fibroblast
    • D. Unilocular adipocyte
    • E. Macrophage
  2. Which connective tissue protein forms tracks that facilitate fibroblast migration during wound healing?

    • A. Fibronectin
    • B. Elastin
    • C. Fibrillin
    • D. Keratin
    • E. Osteocalcin
  3. Which protein is a major component of the microfibrils surrounding elastin?

    • A. Fibronectin
    • B. Laminin
    • C. Fibrillin-1
    • D. Entactin
    • E. Type II collagen
  4. Which connective tissue cell produces immunoglobulins?

    • A. Fibroblast
    • B. Mast cell
    • C. Plasma cell
    • D. Pericyte
    • E. Adipocyte
  5. Which connective tissue cell contains granules rich in heparin and other mediators of inflammation?

    • A. Fibroblast
    • B. Adipocyte
    • C. Mast cell
    • D. Pericyte
    • E. Osteocyte
  6. Which connective tissue cell is commonly located near small blood vessels and contains metachromatic granules?

  7. Which connective tissue cell is derived from a hematopoietic precursor and can become a phagocytic resident cell?

  8. Which extracellular matrix molecule is a sulfated adhesive glycoprotein that can bind type IV collagen and laminin?

  9. Which collagen type forms a network in the basal lamina?

  10. A patient has impaired wound healing and defective collagen maturation due to vitamin C deficiency. Which process is most directly affected?

  11. A child has a connective tissue disorder with abnormal fibrillin and long slender limbs. Which structure is most directly affected?

  12. Which fiber type provides the greatest tensile strength in many connective tissues?

  13. During wound healing, fibroblasts become more metabolically active. Which organelle would be particularly prominent in these cells?

  14. Which cell is the principal resident cell responsible for producing most extracellular matrix components in connective tissue proper?

  15. Which connective tissue fiber is composed primarily of type III collagen?

  16. Which statement best describes reticular fibers?

  17. Which adipocyte contains multiple small lipid droplets and usually has a centrally located nucleus?

  18. Which collagen is most characteristic of cartilage matrix?

  19. Which glycosaminoglycan is unsulfated and can form large proteoglycan aggregates by associating with core proteins?

  20. Which collagen type is associated with anchoring fibrils that secure the basal lamina to underlying connective tissue?

  21. Which connective tissue component is most responsible for resisting compression and binding large amounts of water?

  22. A histologic section shows sparse cells separated by abundant extracellular matrix. This feature is most characteristic of:

  23. Which cell type can differentiate into several mesenchymal lineages and is associated with small blood vessels?

  24. A tissue contains branching fibers that can stretch and recoil. Which component is most responsible?

  25. Which connective tissue cell type normally has a large amount of rough endoplasmic reticulum and Golgi apparatus because of active matrix synthesis?

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