Heart Failure Drugs — Cardiovascular Pharmacology

Heart Failure Drugs MCQs: practice questions

Sample Heart Failure Drugs multiple-choice questions from Cardiovascular Pharmacology.

1. Which recombinant peptide increases cGMP in acute decompensated heart failure?

   • A. Chronic heart failure
   • B. Nesiritide
   • C. Reduction of left-ventricular filling pressure
   • D. Improved cardiac output
   • E. Control of ventricular rate in atrial fibrillation

2. What is the major AV-node effect of digoxin?

   • A. Reduced ventricular rate
   • B. Slows AV-node conduction
   • C. Reduced cardiac workload
   • D. Increased vagal activity
   • E. Reduced sympathetic tone

3. Which pair is used for long-term vasodilator therapy in heart failure?

   • A. ARB and digoxin
   • B. Nitroprusside and nitroglycerin
   • C. Isosorbide dinitrate and hydralazine
   • D. ACE inhibitor and diuretic
   • E. Beta blocker and diuretic

4. Which cardiac glycoside is used in heart failure and atrial arrhythmias?

   • A. Digoxin
   • B. Inamrinone
   • C. Nitroprusside
   • D. Nitroglycerin
   • E. Hydralazine

5. Which inotrope is less useful when severe hypotension is caused by low peripheral resistance?

   • A. Losartan
   • B. Digoxin
   • C. Dobutamine
   • D. Nesiritide
   • E. Milrinone

6. Which inotrope is restricted to IV administration?

7. Which cardiac glycoside is used in the United States according to the source?

8. Which adverse effect is a major concern with potent vasodilators?

9. Which inotrope is administered only intravenously for short-term support?

10. Which statement about digoxin is correct?

11. Which vasodilator has balanced arterial and venous effects?

12. Which diuretic strategy is useful in acute pulmonary edema?

13. Which drug class is frequently combined with an ACE inhibitor in mild CHF?

14. Which adverse effect is important with nesiritide?

15. Which drug increases cAMP-mediated calcium-channel activity in cardiac muscle?

16. Which therapy reduces ventricular filling pressure and is useful in acute pulmonary edema?

17. Which phosphodiesterase inhibitor has positive inotropic and vasodilator effects?

18. Which drug can be combined with nitroglycerin or nitroprusside in advanced heart failure?

19. Which vasodilator has more prominent venous than arterial effects?

20. Which class reduces preload by promoting sodium and water excretion?

21. Which heart-failure drug increases vagal tone and decreases sympathetic tone?

22. Which drug produces positive inotropy without substantially increasing peripheral resistance?

23. Which toxicity can digoxin produce?

24. Which effect of digoxin helps control ventricular rate in atrial fibrillation?

25. Which drug lowers pulmonary capillary wedge pressure through cGMP-mediated effects?

26. Which therapy is particularly useful when heart failure is associated with hypertension or valvular insufficiency?

27. Which pump is inhibited by digoxin?

28. What receptor actions characterize carvedilol?

29. Which drug increases cGMP and stroke volume in acute decompensated heart failure?

30. Which beta blocker has demonstrated morbidity and mortality benefit in heart failure?