General Pharmacology Pharmacology practice questions
This section of the Saturn Medic Pharmacology question bank covers 5 topics under General Pharmacology: Drug Development & Prescription Principles (30 questions); Drug Interactions & Adverse Drug Reactions (30 questions); Pharmacodynamics (30 questions); Pharmacogenetics & Individual Variation (30 questions); and Pharmacokinetics (30 questions).
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General Pharmacology Pharmacology MCQs: mixed practice questions
Try 5 sample questions drawn from across General Pharmacology. Tap an answer to check it.
A patient has stable hepatic failure and is prescribed a drug extensively metabolized by the liver. What prescribing consideration is most important?
From: Drug Development & Prescription PrinciplesCorrect answer: B. Hepatic impairment can reduce metabolism of drugs that depend heavily on hepatic clearance, potentially increasing exposure.A drug is known to inhibit CYP3A. Which outcome is most likely for a second drug that is normally metabolized by CYP3A?
From: Drug Interactions & Adverse Drug ReactionsCorrect answer: A. Inhibiting a metabolic pathway decreases clearance of susceptible substrates and can increase their plasma concentrations.A drug's dose-response curve has the same maximum effect as another drug but is shifted to the right. The right-shifted drug is:
From: PharmacodynamicsCorrect answer: D. A rightward shift means a higher concentration is required to produce the same effect, indicating lower potency.A patient with severe hepatic impairment receives a drug primarily cleared by hepatic metabolism. What may happen?
From: Pharmacogenetics & Individual VariationCorrect answer: A. Hepatic impairment can reduce metabolism and clearance of drugs dependent on hepatic function, increasing exposure.A patient receives a drug with a Vd of 100 L. Which statement is most appropriate?
From: PharmacokineticsCorrect answer: A. A large Vd indicates that relatively little drug remains in plasma compared with the total amount in the body, suggesting extensive tissue distribution.