Clinical Subject Page
Cardiopulmonary Resuscitation (CPR)
ICD-10
Does Not Apply
Specialty
Cardiology
Onset
For Life Threatening Conditions
Reviewed
July 2026
On This Page
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OverviewOverview
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IndicationsIndications
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Initial AssessmentInitial Assessment
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CPR Algorithm (Step-by-Step)CPR Algorithm (Step-by-Step)
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High-Quality CPR PrinciplesHigh-Quality CPR Principles
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Defibrillation & Cardiac RhythmsDefibrillation & Cardiac Rhythms
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ComplicationsComplications
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PrognosisPrognosis
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Key Points / Clinical PearlsKey Points / Clinical Pearls
Overview
Cardiopulmonary resuscitation (CPR) is an emergency life-saving procedure that combines high-quality chest compressions with ventilation to maintain blood circulation and oxygen delivery to vital organs during cardiac arrest until return of spontaneous circulation (ROSC) or advanced care is available.
Indications For Cardiopulmonary Resuscitation (CPR)
- Unresponsive patient
- No normal breathing (or only gasping)
- No definite pulse within 10 seconds
- Witnessed or suspected cardiac arrest
Common Causes of Cardiac Arrest
- Ventricular fibrillation (VF)
- Pulseless ventricular tachycardia (pVT)
- Pulseless electrical activity (PEA)
- Asystole
- Acute myocardial infarction
- Severe hypoxia
- Massive pulmonary embolism
Initial Assessment
Step 1: Ensure Scene Safety
Ensure the environment is safe before approaching the patient.
Step 2: Check Responsiveness
Tap the patient’s shoulders and shout loudly:
“Are you okay?”
Step 3: Call for Help
- Activate the Emergency Medical Services (EMS) by calling your local emergency number (e.g., 911, 999, 112).
- Ask someone to bring an Automated External Defibrillator (AED) if one is available.
Step 4: Check Breathing & Pulse
Assess breathing and check for a pulse simultaneously for no more than 10 seconds.
If the patient has no pulse and is not breathing normally (or is only gasping), begin CPR immediately.
Step 5: Begin CPR
Start high-quality chest compressions immediately while waiting for the Emergency Medical Services (EMS) and the Automated External Defibrillator (AED) to arrive.
Cardiopulmonary Resuscitation (CPR) Algorithm (Step-by-Step)
Adult Cardiopulmonary Resuscitation (CPR)
- Ensure scene safety.
- Check responsiveness.
- Activate EMS & obtain AED.
- Check breathing and pulse (≤10 sec).
- Start chest compressions.
- Open the airway.
- Give rescue breaths.
- Attach AED/defibrillator.
- Analyze rhythm.
- Deliver shock if indicated.
- Resume CPR immediately for 2 minutes.
- Repeat rhythm checks until ROSC or resuscitation is terminated.
Compression : Ventilation Ratio
- 30 : 2 → One rescuer (adult)
- 30 : 2 → Two rescuers (adult)
- 15 : 2 → Two rescuers (infants & children)
High-Quality CPR Principles
Chest Compressions
- Rate: 100–120/min
- Depth: 5–6 cm (2–2.4 inches)
- Allow complete chest recoil
- Minimize interruptions (<10 sec)
- Change compressor every 2 minutes
Ventilation
- 2 breaths after every 30 compressions
- Each breath over 1 second
- Visible chest rise
- Avoid excessive ventilation
Defibrillation & Cardiac Rhythms
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Stents
- Drug-eluting stent (DES) (preferred)
- Bare-metal stent (BMS) (rarely used)
Other Devices
- Balloon catheter
- Guidewire
- Guiding catheter
- Intravascular ultrasound (IVUS)
- Optical coherence tomography (OCT)
- Rotational atherectomy
- Intravascular lithotripsy (selected calcified lesions)
Complications
- Rib fractures
- Sternal fracture
- Pneumothorax
- Internal organ injury (rare)
- Gastric inflation and aspiration
- Hypoxic brain injury
- Death if ROSC is not achieved
Prognosis
- Best when Cardiopulmonary Resuscitation (CPR) is started immediately.
- Early defibrillation greatly improves survival.
- Prognosis depends on the cause of cardiac arrest and time to ROSC.
- Delayed CPR is associated with poor neurological outcomes and increased mortality.
Key Points / Clinical Pearls
- Start Cardiopulmonary Resuscitation (CPR) immediately when cardiac arrest is recognized.
- Push hard and fast (100–120 compressions/min).
- Minimize interruptions in chest compressions.
- Use an Automated External Defibrillator (AED) as soon as it becomes available.
- Treat reversible causes (Hs & Ts) during advanced life support.
- Early CPR and early defibrillation are the strongest predictors of survival.
- Goyal A, Singh B, Patel PH. National Center for Biotechnology Information (NIH). Cardiopulmonary Resuscitation, StatPearls.
- Panchal AR, Bartos JA, Cabañas JG, et al. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for CPR and Emergency Cardiovascular Care. Circulation. 2020;142:S366-S468. doi: 10.1161/CIR.0000000000000916.
- National Center for Biotechnology Information (NIH). Advanced Cardiac Life Support (ACLS), StatPearls.
- Cummins RO. Emergency Medical Services and Sudden Cardiac Arrest: The "Chain of Survival" Concept. Annu Rev Public Health. 1993;14:313-333. PMID: 8323592.
- MedlinePlus, National Library of Medicine (NIH). CPR: Health Topic.