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Antiplatelet & Thrombolytic Drugs — Hematology & GI Pharmacology
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Antiplatelet & Thrombolytic Drugs
Hematology & GI Pharmacology · Antiplatelet & Thrombolytic Drugs · medium
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Antiplatelet & Thrombolytic Drugs MCQs: practice questions
Sample Antiplatelet & Thrombolytic Drugs multiple-choice questions from Hematology & GI Pharmacology.
Which antiplatelet drug irreversibly inhibits platelet cyclooxygenase and decreases thromboxane A2 production?
- A. Warfarin
- B. Aspirin
- C. Dipyridamole
- D. Heparin
- E. Alteplase
Which thrombolytic is a recombinant fragment of human tPA?
- A. Streptokinase
- B. Urokinase
- C. Reteplase
- D. Heparin
- E. Warfarin
Which thrombolytic acts on both circulating plasminogen and fibrin-bound plasminogen?
- A. Warfarin
- B. Reteplase
- C. Alteplase
- D. Tenecteplase
- E. Streptokinase
Which agent prevents fibrinogen-mediated platelet aggregation by blocking the final common platelet aggregation receptor?
- A. Abciximab
- B. Alteplase
- C. Vitamin K
- D. Warfarin
- E. Heparin
Which drug inhibits platelet aggregation rather than directly dissolving an existing fibrin clot?
- A. Clopidogrel
- B. Reteplase
- C. Alteplase
- D. Streptokinase
- E. Urokinase
Which adverse effect is especially important when GPIIb/IIIa inhibitors are combined with heparin?
Which agent is used to reduce platelet aggregation by inhibiting ADP-mediated activation?
What is the principal adverse effect of GPIIb/IIIa inhibitors?
Which P2Y12 inhibitor has the same mechanism as ticlopidine but fewer adverse effects and a very low frequency of neutropenia?
Which drug is used during percutaneous coronary intervention and is administered by infusion as a GPIIb/IIIa inhibitor?
Which thrombolytic is a bacterial protein that activates plasminogen nonenzymatically?
Which enzyme directly degrades fibrin in the fibrinolytic pathway?
Which platelet receptor is directly targeted by abciximab?
Which thrombolytic has a half-life long enough to permit bolus administration?
Which adverse effect is common to all thrombolytic drugs?
Which thrombolytic is derived from streptococci?
Which drug is a direct platelet inhibitor rather than an anticoagulant?
Which antiplatelet drug is a platelet COX inhibitor?
Which drug is a chimeric monoclonal antibody fragment?
Which treatment most directly promotes fibrin clot dissolution?
Which thrombolytics are engineered forms of human tPA with longer half-lives?
Which thrombolytic is most specific for fibrin-bound plasminogen?
Which GPIIb/IIIa inhibitor is a small synthetic peptide?
Which antiplatelet class blocks the platelet ADP P2Y12 receptor?
Which thrombolytic is recombinant human tissue plasminogen activator?
Which drug is a peptide mimetic that binds platelet GPIIb/IIIa?
Which antithrombotic agent impairs fibrin polymerization and platelet function in vivo by an unclear mechanism?
Which drug is a GPIIb/IIIa inhibitor?
What is the immediate precursor activated by thrombolytic therapy to generate plasmin?
Which thrombolytic is produced in the kidney and activates plasminogen?