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Antiulcer & Acid-Suppressing Drugs — Hematology & GI Pharmacology

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Question Bank Pharmacology Hematology & GI Pharmacology Antiulcer & Acid-Suppressing Drugs
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Antiulcer & Acid-Suppressing Drugs
Hematology & GI Pharmacology · Antiulcer & Acid-Suppressing Drugs · medium
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Antiulcer & Acid-Suppressing Drugs MCQs: practice questions

Sample Antiulcer & Acid-Suppressing Drugs multiple-choice questions from Hematology & GI Pharmacology.

  1. Which drug is a prostaglandin analogue used specifically to prevent NSAID-induced mucosal injury?

    • A. Famotidine
    • B. Misoprostol
    • C. Omeprazole
    • D. Bismuth subsalicylate
    • E. Sucralfate
  2. Which drug is a histamine H2-receptor antagonist?

    • A. Bismuth subsalicylate
    • B. Famotidine
    • C. Omeprazole
    • D. Sucralfate
    • E. Misoprostol
  3. Which adverse effect distinguishes aluminum hydroxide from magnesium hydroxide in antacid therapy?

    • A. Bronchospasm
    • B. Nephrotoxicity in all patients
    • C. Constipation
    • D. Diarrhea
    • E. Tinnitus
  4. Which antacid is contraindicated in hypertension because of its sodium content?

    • A. Calcium carbonate
    • B. Aluminum hydroxide
    • C. Sucralfate
    • D. Sodium bicarbonate
    • E. Magnesium hydroxide
  5. Which treatment combines a proton pump inhibitor with antibiotics to eradicate H. pylori?

    • A. Triple therapy
    • B. Dual antiplatelet therapy
    • C. Warfarin bridging
    • D. Thrombolytic therapy
    • E. Erythropoietin therapy
  6. Which proton pump inhibitor is FDA approved to reduce stress-related mucosal bleeding?

  7. Which drug binds ulcerated tissue rather than primarily suppressing acid secretion?

  8. Which drug is a proton pump inhibitor rather than an H2 blocker?

  9. Which antacid is associated with diarrhea and should be balanced with aluminum hydroxide in combination preparations?

  10. Which adverse effect is associated with magnesium-containing antacids?

  11. Which drug is added to some H. pylori regimens as a mucosal-protective agent?

  12. When should proton pump inhibitors ideally be administered to optimize absorption?

  13. Which adverse effect can result from excessive gastric acid suppression with proton pump inhibitors?

  14. Which H2 blocker is a competitive inhibitor of cytochrome P450 and can increase warfarin half-life?

  15. Which acid-suppressing drug is the most effective class for treatment of GERD?

  16. Which drug class decreases both basal and meal-stimulated gastric acid secretion?

  17. Which adverse effect is associated with aluminum-containing antacids?

  18. Which H2 blocker is less likely than cimetidine to produce major CYP-mediated drug interactions?

  19. Which drug is an H2 blocker rather than a proton pump inhibitor?

  20. Which drug irreversibly inhibits the gastric H+/K+-ATPase?

  21. Which drug can increase protective mucus and bicarbonate production in the gastric mucosa?

  22. Which drug is specifically useful for patients who have failed H2-blocker therapy?

  23. Which agent is a direct neutralizer of gastric acid rather than an inhibitor of acid secretion?

  24. Which acid-suppressing agent is combined with antimicrobial drugs in standard eradication regimens for Helicobacter pylori?

  25. Which drug is most directly associated with cytochrome P450 inhibition among the H2 blockers listed?

  26. Which antacid is a salt-containing osmotic agent when used in the lower GI tract rather than an upper-GI acid suppressant?

  27. Which drug is useful in hyper-acid-secreting gastrinomas?

  28. Which drug is used to prevent NSAID-induced ulcers by reducing acid secretion and increasing mucosal protection?

  29. Which drug class blocks histamine-mediated stimulation of gastric parietal cells?

  30. Which mucosal protective drug has affinity for exposed proteins in the crater of a duodenal ulcer?

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