WBC Disorders & Leukemia — Hematopathology

WBC Disorders & Leukemia MCQs: practice questions

Sample WBC Disorders & Leukemia multiple-choice questions from Hematopathology.

1. Basophilia is particularly associated with:

   • A. Iron deficiency
   • B. Multiple sclerosis
   • C. Chronic myeloid leukemia
   • D. Minimal change disease
   • E. Osteosarcoma

2. Auer rods are characteristic of:

   • A. Mature lymphocytes
   • B. Mature B cells
   • C. Plasma cells
   • D. Myeloid blasts
   • E. Megakaryocytes

3. Neutropenia increases the risk of:

   • A. Hemarthrosis
   • B. Bacterial and fungal infections
   • C. Gallstones
   • D. Hyperthyroidism
   • E. Osteoarthritis

4. T-cell ALL commonly presents with a:

   • A. Pancreatic mass
   • B. Renal mass
   • C. Mediastinal mass
   • D. Bladder tumor
   • E. Bone cyst

5. B-cell ALL commonly shows abnormalities involving:

   • A. PML::RARA only
   • B. ETV6::RUNX1 or other recurrent genetic lesions
   • C. BCR::ABL1 in every case
   • D. MYC amplification in every case
   • E. RET mutation only

6. A blast count of at least 20% in blood or marrow generally supports the diagnosis of:

7. The Philadelphia chromosome results from:

8. A common feature of acute leukemia is:

9. Chronic myeloid leukemia is associated with:

10. Polycythemia vera is commonly associated with:

11. Atypical lymphocytes in infectious mononucleosis are primarily:

12. Acute myeloid leukemia is characterized by:

13. Myelofibrosis commonly produces:

14. Acute promyelocytic leukemia has a major clinical association with:

15. Hairy cell leukemia commonly causes:

16. Infectious mononucleosis is most commonly caused by:

17. A common cause of reactive neutrophilia is:

18. Hairy cell leukemia is characteristically associated with:

19. Essential thrombocythemia is characterized by persistent elevation of:

20. Leukemoid reaction differs from CML because it is:

21. Myelodysplastic syndromes are characterized by:

22. Acute promyelocytic leukemia is associated with:

23. An increased absolute neutrophil count is called:

24. Eosinophilia is classically associated with:

25. A classic peripheral smear finding in CLL is:

26. Acute leukemia commonly presents with:

27. Acute lymphoblastic leukemia is the most common acute leukemia in:

28. The leukocyte lineage of a blast can be established using:

29. Chronic lymphocytic leukemia is characterized by proliferation of:

30. Chronic myeloid leukemia can transform into: