Glomerular Disease — Renal & Genitourinary

Glomerular Disease MCQs: practice questions

Sample Glomerular Disease multiple-choice questions from Renal & Genitourinary.

1. Granulomatosis with polyangiitis is commonly associated with:

   • A. PR3-ANCA
   • B. Anti-PLA2R antibodies
   • C. Anti-CCP antibodies
   • D. Anti-centromere antibodies
   • E. Anti-GBM antibodies only

2. Diabetic nephropathy classically produces:

   • A. Papillary tumors
   • B. Diffuse interstitial granulomas
   • C. Mesangial expansion and nodular glomerulosclerosis
   • D. Medullary necrosis only
   • E. Crescents only

3. IgA nephropathy typically presents with:

   • A. Hematuria only decades after infection
   • B. Nephrotic syndrome after years of diabetes only
   • C. Renal colic after meals
   • D. Polyuria with hypercalcemia
   • E. Recurrent hematuria occurring shortly after an upper respiratory infection

4. The most common cause of nephrotic syndrome in children is:

   • A. Amyloidosis
   • B. Focal segmental glomerulosclerosis
   • C. Diabetic nephropathy
   • D. Membranous nephropathy
   • E. Minimal change disease

5. The characteristic immune deposit in IgA nephropathy is:

   • A. IgE in the interstitium
   • B. IgA in the mesangium
   • C. IgM in tubules
   • D. IgG in the subepithelial space only
   • E. C3 in renal arteries only

6. The characteristic immunofluorescence pattern in membranous nephropathy is:

7. Membranoproliferative glomerulonephritis commonly shows:

8. Minimal change disease usually shows which finding on light microscopy?

9. Which finding is most characteristic of nephritic syndrome?

10. Alport syndrome results from abnormalities in:

11. Minimal change disease is characterized on electron microscopy by:

12. Crescents in rapidly progressive glomerulonephritis are primarily composed of:

13. Goodpasture syndrome classically affects the:

14. Goodpasture syndrome is caused by antibodies directed against:

15. Minimal change disease is strongly associated with:

16. Which condition is a recognized secondary association of focal segmental glomerulosclerosis?

17. Rapidly progressive glomerulonephritis is characterized clinically by:

18. The nodular glomerular lesion of advanced diabetic nephropathy is called:

19. The immunofluorescence pattern in poststreptococcal glomerulonephritis is typically:

20. A classic 'tram-track' appearance in glomerular capillary walls can be seen in:

21. Microscopic polyangiitis is commonly associated with:

22. Poststreptococcal glomerulonephritis classically follows infection with:

23. Focal segmental glomerulosclerosis is defined by sclerosis involving:

24. A patient develops edema, heavy proteinuria, hypoalbuminemia, and hyperlipidemia. Which renal syndrome is present?

25. Amyloidosis causes renal disease through deposition of amyloid in the:

26. Alport syndrome commonly includes renal disease with:

27. Membranous nephropathy is characterized by:

28. A classic antigen target in primary membranous nephropathy is:

29. Renal amyloid deposits are identified histologically by:

30. Poststreptococcal glomerulonephritis typically shows on electron microscopy: