Renal Tumors — Renal & Genitourinary

Renal Tumors MCQs: practice questions

Sample Renal Tumors multiple-choice questions from Renal & Genitourinary.

1. Papillary renal cell carcinoma is associated with alterations involving:

   • A. RET exclusively
   • B. APC exclusively
   • C. MET signaling
   • D. RB1 exclusively
   • E. VHL exclusively

2. Renal cell carcinoma commonly arises from epithelial cells of the:

   • A. Proximal tubule
   • B. Collecting duct only
   • C. Glomerular podocytes
   • D. Ureteral smooth muscle
   • E. Renal pelvis cartilage

3. A key distinction between angiomyolipoma and renal cell carcinoma is that angiomyolipoma contains:

   • A. Amyloid fibrils
   • B. Malignant osteoid
   • C. Urothelial carcinoma cells
   • D. Glomerular crescents
   • E. Mature adipose tissue

4. Chromophobe renal cell carcinoma commonly arises from:

   • A. Glomerular endothelial cells
   • B. Podocytes
   • C. Proximal tubular cells exclusively
   • D. Intercalated cells of the collecting duct
   • E. Urothelial cells

5. Which renal tumor is usually benign and often discovered incidentally?

   • A. Renal medullary carcinoma
   • B. Collecting duct carcinoma
   • C. Clear cell RCC
   • D. Oncocytoma
   • E. Wilms tumor

6. Renal cell carcinoma commonly metastasizes to the:

7. Renal cell carcinoma has a tendency to invade the:

8. Renal cell carcinoma can produce paraneoplastic:

9. Which renal carcinoma is characterized by multiple bilateral tumors in some patients with hereditary papillary renal carcinoma?

10. The most common malignant renal tumor in adults is:

11. A renal oncocytoma is composed of cells with abundant:

12. A large renal mass with hemorrhage and necrosis in an adult is concerning for:

13. The most common histologic subtype of renal cell carcinoma is:

14. Clear cell renal cell carcinoma is commonly associated with alterations involving:

15. Collecting duct carcinoma is generally considered:

16. Chromophobe renal cell carcinoma typically has:

17. Clear cell renal cell carcinoma is characterized microscopically by tumor cells with:

18. Angiomyolipoma is strongly associated with:

19. A classic clinical manifestation of renal cell carcinoma is:

20. A classic histologic pattern in Wilms tumor is the:

21. Renal medullary carcinoma is strongly associated with:

22. Another important paraneoplastic manifestation of renal cell carcinoma is:

23. Wilms tumor is primarily a tumor of:

24. Papillary renal cell carcinoma is often characterized histologically by:

25. A renal mass with macroscopic fat strongly suggests:

26. A renal tumor composed of primitive blastemal cells is most characteristic of:

27. Which benign renal tumor is composed of mature adipose tissue, smooth muscle, and blood vessels?

28. Wilms tumor may be associated with congenital anomalies such as:

29. Wilms tumor is associated with abnormalities involving:

30. The classic triad of renal cell carcinoma includes hematuria, flank pain, and: