Thyroid Pathology — Endocrine

Thyroid Pathology MCQs: practice questions

Sample Thyroid Pathology multiple-choice questions from Endocrine.

1. Follicular thyroid carcinoma commonly metastasizes to:

   • A. Only liver
   • B. Only skin
   • C. Only brain
   • D. Bone and lungs
   • E. Only lymph nodes

2. The most aggressive thyroid carcinoma is:

   • A. Anaplastic thyroid carcinoma
   • B. Follicular adenoma
   • C. Medullary carcinoma
   • D. Follicular carcinoma
   • E. Papillary carcinoma

3. RET mutations are strongly associated with:

   • A. Anaplastic carcinoma only
   • B. Medullary thyroid carcinoma
   • C. Papillary carcinoma in every case
   • D. Follicular adenoma
   • E. Hashimoto thyroiditis

4. A major risk factor for papillary thyroid carcinoma is exposure to:

   • A. Chronic iron deficiency
   • B. Hypercalcemia
   • C. Vitamin B12 excess
   • D. Ionizing radiation
   • E. Gout

5. Hashimoto thyroiditis increases the risk of:

   • A. Pheochromocytoma
   • B. Thyroid MALT lymphoma
   • C. Medulloblastoma
   • D. Osteosarcoma
   • E. Renal cell carcinoma

6. A thyroid follicular adenoma is distinguished from follicular carcinoma by absence of:

7. Medullary thyroid carcinoma arises from:

8. MEN 2A includes medullary thyroid carcinoma, pheochromocytoma, and:

9. Follicular thyroid carcinoma is more likely than papillary carcinoma to spread by:

10. The most common thyroid malignancy is:

11. Thyroid lymphoma is most strongly associated with:

12. Medullary thyroid carcinoma is a component of:

13. Papillary thyroid carcinoma classically shows:

14. Myxedema is associated with severe:

15. Thyroid storm is a severe manifestation of:

16. The most important tumor marker used in follow-up of differentiated thyroid carcinoma is:

17. Hashimoto thyroiditis is associated with antibodies against:

18. MEN 2B is associated with medullary thyroid carcinoma and:

19. A multinodular goiter is characterized by:

20. The diagnosis of follicular thyroid carcinoma requires evidence of:

21. A patient with hypothyroidism may develop:

22. The characteristic thyroid histology in Graves disease includes:

23. Medullary thyroid carcinoma produces:

24. Anaplastic thyroid carcinoma usually occurs in:

25. A characteristic stromal component of medullary thyroid carcinoma is:

26. A thyroid nodule composed of follicles filled with colloid is most consistent with:

27. Graves disease is caused by antibodies that:

28. Papillary thyroid carcinoma commonly spreads through:

29. Papillary thyroid carcinoma may contain:

30. A toxic multinodular goiter produces: