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Sulfonamides & Trimethoprim — Antimicrobial Pharmacology II
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Sulfonamides & Trimethoprim
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Sulfonamides & Trimethoprim MCQs: practice questions
Sample Sulfonamides & Trimethoprim multiple-choice questions from Antimicrobial Pharmacology II.
Which sulfonamide is specifically used as a topical agent in burn treatment?
- A. Silver sulfadiazine
- B. Sulfasalazine
- C. Sulfisoxazole
- D. Sulfacetamide
- E. Trimethoprim
Which neonatal complication can result from sulfonamide displacement of bilirubin from albumin?
- A. Gray baby syndrome
- B. Neonatal hypoglycemia
- C. Respiratory distress syndrome
- D. Kernicterus
- E. Neonatal tetany
Which hematologic toxicity is increased in patients with G6PD deficiency receiving sulfonamides?
- A. Polycythemia
- B. Thrombocytosis
- C. Hemolytic anemia
- D. Iron deficiency only
- E. Neutrophilia
Which statement best describes the combination of trimethoprim and sulfamethoxazole?
- A. It inhibits sequential steps in bacterial DNA replication
- B. It blocks two ribosomal subunits
- C. It inhibits sequential steps in bacterial folate synthesis
- D. It inhibits fungal ergosterol synthesis
- E. It inhibits bacterial cell-wall cross-linking
Which sulfonamide is used topically for ocular infections?
- A. Sulfacetamide
- B. Trimethoprim
- C. Dapsone
- D. Sulfamethoxazole
- E. Sulfisoxazole
Which drug class is bacteriostatic because it blocks synthesis of dihydrofolic acid?
Which adverse reaction can occur with sulfonamides in patients with G6PD deficiency?
Which mechanism explains resistance to sulfonamides?
Which sulfonamide is used for Nocardia infections?
Which class can cause nausea, vomiting, photosensitivity, and serum sickness reactions?
Which bacterial metabolite is structurally mimicked by sulfonamides?
Which serious skin reaction can occur with sulfonamides?
Which bacterial enzyme is inhibited downstream of dihydropteroate synthase by trimethoprim?
Which drug is a folate antagonist at dihydrofolate reductase rather than dihydropteroate synthase?
Which adverse effect can occur with sulfonamides due to photosensitivity?
Which combination is used to treat Pneumocystis jirovecii pneumonia?
Which class has structural similarity to PABA?
Which enzyme is inhibited by sulfonamides?
Which sulfonamide is used topically for burns?
Which sulfonamide is used for inflammatory bowel disease?
Which adverse effect can occur from trimethoprim/sulfamethoxazole because of the sulfonamide component?
Which combination is commonly used for Pneumocystis prophylaxis in immunosuppressed patients?
Which combination is bactericidal because it blocks two sequential steps in bacterial folate metabolism?
Which drug is a second-line treatment for Pneumocystis pneumonia and a first-line treatment for leprosy?
Which drug inhibits bacterial dihydrofolate reductase?
Which adverse effect of sulfonamides is particularly dangerous during pregnancy because of bilirubin displacement?
Which agent is structurally related to sulfonamides and used for leprosy?
Why is trimethoprim combined with sulfamethoxazole?
Which class can potentiate the effects of oral anticoagulants by displacement from albumin?
What is the usual effect of sulfonamides when used alone?