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Anxiolytics & Sedative-Hypnotics — CNS Pharmacology

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Anxiolytics & Sedative-Hypnotics
CNS Pharmacology · Anxiolytics & Sedative-Hypnotics · medium
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Anxiolytics & Sedative-Hypnotics MCQs: practice questions

Sample Anxiolytics & Sedative-Hypnotics multiple-choice questions from CNS Pharmacology.

  1. Which benzodiazepine-related adverse effect is particularly important in older adults?

    • A. CNS depression and sedation
    • B. Severe agranulocytosis
    • C. Hyperprolactinemia
    • D. Cholestatic jaundice
    • E. Gingival hyperplasia
  2. Which barbiturate is used as an anticonvulsant?

    • A. Pentobarbital
    • B. Secobarbital
    • C. Phenobarbital
    • D. Amobarbital
    • E. Thiopental
  3. Which nonbenzodiazepine hypnotic is also listed for insomnia?

    • A. Eszopiclone
    • B. Buspirone
    • C. Flumazenil
    • D. Phenobarbital
    • E. Diazepam
  4. Which drug is associated with dizziness and fatigue among melatonin receptor agonists?

    • A. Buspirone
    • B. Phenobarbital
    • C. Ramelteon
    • D. Flumazenil
    • E. Diazepam
  5. Which class prolongs the duration of GABA-induced chloride-channel opening?

    • A. Benzodiazepines
    • B. SSRIs
    • C. SNRIs
    • D. Barbiturates
    • E. MAOIs
  6. Which benzodiazepine is particularly useful for status epilepticus?

  7. Which condition can prolong the action of barbiturates?

  8. After abrupt discontinuation, withdrawal is generally sooner and more severe with which benzodiazepines?

  9. Which effect is characteristic of barbiturate overdose?

  10. Which drug is the benzodiazepine receptor antagonist?

  11. Which barbiturate can precipitate acute intermittent porphyria?

  12. Which anxiolytic is preferred when a nonsedating agent is desired?

  13. Which sedative-hypnotic is largely supplanted by benzodiazepines for sedation and hypnosis?

  14. Which benzodiazepine is included among drugs used to treat anxiety disorders?

  15. Which drug would be most appropriate for chronic anxiety when sedation and dependence are concerns?

  16. Which barbiturate effect results from induction of hepatic microsomal enzymes during long-term use?

  17. Which drug is another nonbenzodiazepine hypnotic with a short duration of action?

  18. Which benzodiazepine is commonly used for anxiety and is also an antiepileptic drug?

  19. Which anxiolytic is a 5-HT1A agonist?

  20. Which class is associated with tolerance and physical dependence when used chronically?

  21. Which drug class is generally preferred over barbiturates for treatment of anxiety and sleep disorders because of a better safety profile?

  22. Which barbiturate is used for intravenous general anesthesia?

  23. Which class can produce GABA-mimetic activity at high doses?

  24. Which drug is a melatonin receptor agonist used for sleep disorders?

  25. Which intervention is part of treatment for severe phenobarbital overdose?

  26. Which sedative-hypnotic is a nonbenzodiazepine that acts at the benzodiazepine receptor complex?

  27. Which drug directly antagonizes the benzodiazepine receptor site rather than enhancing GABA activity?

  28. What is a major reason barbiturates are less commonly used than benzodiazepines for anxiety and insomnia?

  29. Which class enhances GABA-mediated inhibition by increasing the frequency of chloride-channel opening?

  30. Which drug is used for withdrawal syndrome from sedative-hypnotic drugs?

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