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Thyroid Drugs — Endocrine Pharmacology
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Thyroid Drugs
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Thyroid Drugs MCQs: practice questions
Sample Thyroid Drugs multiple-choice questions from Endocrine Pharmacology.
Which effect of iodide contributes to its use before thyroid surgery?
- A. Increasing thyroid vascularity
- B. Increasing T3 release
- C. Stimulating thyroid growth
- D. Firming of thyroid tissue and decreased vascularity
- E. Increasing TSH secretion
Which thyroid hormone is the most important ligand for the thyroid receptor?
- A. T4
- B. TSH
- C. TRH
- D. Reverse T3
- E. T3
Which major toxicity limits the use of anion inhibitors of thyroid function?
- A. Severe hypoglycemia
- B. Severe aplastic anemia
- C. Osteonecrosis
- D. Pulmonary edema
- E. Hypercalcemia
Which thyroid hormone preparation is synthetic T3?
- A. Levothyroxine
- B. Liothyronine
- C. Liotrix
- D. Thyroid USP
- E. Radioactive iodine-131
What is the Wolff-Chaikoff effect?
- A. Low iodide stimulates T3 conversion
- B. Iodide directly activates TSH receptors
- C. High intracellular iodide inhibits thyroid hormone biosynthesis
- D. Radioiodine stimulates thyroid growth
- E. Iodide blocks all peripheral deiodination
Which treatment is contraindicated during pregnancy because of radiation to the fetal thyroid?
Which thyroid drug class is eliminated mainly in the urine as glucuronides?
Which cardiovascular adverse effect can thyroid hormone precipitate in susceptible patients?
Which serious hematologic adverse effect can occur with thioamides?
Which ion competitively inhibits iodide transport into the thyroid gland?
Which thioamide is approximately 10 times more potent than propylthiouracil?
Which thyroid hormone has the longer half-life?
Which thyroid drug is most likely to cause hyperthyroidism if given in excessive doses?
Which treatment decreases thyroid hormone release and is usually combined with a thioamide?
How do thyroid hormones exert their principal genomic effects?
Which thyroid hormone preparation is synthetic T4?
Which drug is used in thyroid storm to inhibit thyroid hormone synthesis and peripheral T4-to-T3 conversion?
Which adverse effect can occur with iodide therapy?
Which preparation is a 4:1 mixture of T4 and T3?
Which adverse effect can result from excessive thyroid hormone replacement?
Which drug is used as a replacement therapy for hypothyroidism?
Which thioamide can be used during pregnancy?
Which thyroid hormone preparation is generally preferred over animal thyroid USP for initial therapy?
How long may it take to attain euthyroid status after starting thioamide therapy?
Which mechanism best describes radioactive iodine therapy?
Which enzyme is inhibited by thioamides?
Why does thioamide treatment not immediately normalize thyroid hormone levels?
Which thioamide also inhibits peripheral conversion of T4 to T3?
What is the approximate radioactive half-life of iodine-131?
Which radioactive isotope is used to ablate hyperactive thyroid tissue?