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Insulin & Diabetes Drugs — Endocrine Pharmacology
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Insulin & Diabetes Drugs
Endocrine Pharmacology · Insulin & Diabetes Drugs · medium
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Insulin & Diabetes Drugs MCQs: practice questions
Sample Insulin & Diabetes Drugs multiple-choice questions from Endocrine Pharmacology.
Which serious metabolic complication can occur with SGLT2 inhibitors even when plasma glucose is not markedly elevated?
- A. Lactic acidosis
- B. Hyperosmolar hyperglycemic state
- C. Euglycemic diabetic ketoacidosis
- D. Acute adrenal crisis
- E. Severe respiratory alkalosis
Which antidiabetic class is ineffective in type 1 diabetes because it requires functioning pancreatic β-cells?
- A. Biguanines
- B. α-Glucosidase inhibitors
- C. Thiazolidinediones
- D. Sulfonylureas
- E. DPP-IV inhibitors
Which hemodynamic effect can occur after initiation of an SGLT2 inhibitor?
- A. Marked fluid retention
- B. Severe hypertension
- C. Pulmonary edema
- D. Volume depletion and hypotension
- E. Hypervolemia from increased sodium retention
Which serious adverse effect is associated with metformin?
- A. Severe hypokalemia
- B. Agranulocytosis
- C. Lactic acidosis
- D. Osteomalacia
- E. Pulmonary fibrosis
Which oral antidiabetic drug reduces hepatic glucose production and increases peripheral insulin sensitivity?
- A. Glyburide
- B. Metformin
- C. Acarbose
- D. Pioglitazone
- E. Repaglinide
Which drug can improve glycemic control in type II diabetes while also lowering serum androgens in polycystic ovary syndrome?
Which tissue response is produced by thiazolidinediones?
What is the principal renal effect of SGLT2 inhibition?
Which α-glucosidase inhibitor is more potent against sucrase and maltase than acarbose?
Which agent is a GLP-1 analog used by subcutaneous injection?
Which adverse effect is particularly associated with SGLT2 inhibitors because of increased urinary glucose?
Which enzyme is inhibited by sitagliptin?
Which meglitinide has a more rapid onset and greater specificity for pancreatic potassium channels?
Which insulin preparation has a 14-carbon fatty acid attached to its A chain?
Where do SGLT2 inhibitors exert their primary renal action?
Which antidiabetic drug class is administered orally and commonly causes headache and nausea?
Which adverse effect limits thiazolidinedione use in patients with heart failure?
Which insulin preparation has an onset of about 1.5 hours and a duration of about 24 hours?
Which drugs inhibit pancreatic α-amylase and intestinal α-glucosidase?
Which drug inhibits the sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule?
Which electrolyte abnormality can occur with insulin therapy?
Which adverse effect is relatively uncommon with α-glucosidase inhibitors?
Which serious adverse effect has been observed with incretin mimetics?
Which adverse effect most commonly limits meglitinide therapy?
Which insulin preparation has an onset of approximately 15 minutes and a duration of 3–5 hours?
Which intracellular receptor is activated by thiazolidinediones?
Which insulin-associated problem can occur at an injection site after repeated administration?
Which adverse effect is most directly caused by excessive insulin administration?
Which insulin preparation can be administered intravenously?
Which effect is produced by GLP-1 receptor agonists?