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Drugs Affecting Bone & Calcium — Endocrine Pharmacology
Pharmacology Question Bank
Pharmacology Question Bank
Drugs Affecting Bone & Calcium
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Drugs Affecting Bone & Calcium MCQs: practice questions
Sample Drugs Affecting Bone & Calcium multiple-choice questions from Endocrine Pharmacology.
Which calcitonin preparation has a longer half-life than human calcitonin?
- A. Human calcitonin
- B. Teriparatide
- C. Calcitriol
- D. Denosumab
- E. Synthetic salmon calcitonin
Which drug activates the calcium-sensing receptor to reduce PTH secretion?
- A. Teriparatide
- B. Calcitonin
- C. Denosumab
- D. Cinacalcet
- E. Alendronate
Which monoclonal antibody blocks RANKL?
- A. Teriparatide
- B. Denosumab
- C. Calcitonin
- D. Alendronate
- E. Cinacalcet
What is the effect of intermittent PTH exposure on bone?
- A. Net bone resorption
- B. No change in bone turnover
- C. Net bone formation
- D. Complete osteoclast activation
- E. Osteomalacia
Which patient is an approved target population for denosumab?
- A. A patient with acute hypoglycemia
- B. A patient with hyperthyroidism requiring ablation
- C. A postmenopausal woman with osteoporosis
- D. A patient with thyroid storm
- E. A patient with type 1 diabetes requiring insulin
Which bisphosphonate is particularly associated with esophageal irritation and erosion?
What enzyme is inhibited by aminobisphosphonates?
Which is the major adverse effect of cinacalcet?
Which active vitamin D metabolite is 1,25-(OH)2D3?
Which hormone is secreted by thyroid perifollicular cells in response to elevated plasma calcium?
What is the mechanism of non-nitrogenous bisphosphonates such as etidronate?
What is the effect of continuous PTH exposure on bone?
What is the basic chemical relationship between bisphosphonates and pyrophosphate?
Which drug is recombinant human PTH 1–34?
Which vitamin D metabolite increases intestinal calcium absorption?
Which administration route is available for salmon calcitonin?
How is teriparatide administered for osteoporosis?
Which adverse effect is associated with teriparatide?
Why are oral bisphosphonates administered on an empty stomach with water?
Which mineral excretion is increased by calcitonin?
Which vitamin D analog is used for hyperparathyroidism secondary to renal failure without increasing intestinal calcium absorption?
What is the principal effect of calcitonin on osteoclasts?
Which first-generation bisphosphonate is non-nitrogenous?
Which vitamin D analog is a potent suppressor of PTH and is useful in renal or primary hyperparathyroidism?
Which hormone increases renal calcium reabsorption while decreasing renal phosphate reabsorption?
Which rare adverse effect can occur after prolonged bisphosphonate therapy?
What is the principal skeletal action of bisphosphonates?
Which bisphosphonate can be administered once yearly by infusion?
Which drug is useful for hypercalcemia and can reduce plasma calcium within about 2 hours?
Which vitamin D analog is used topically for psoriasis?