Clinical Subject Page
Large Bowel Obstruction
Large Bowel Obstruction is a mechanical or functional blockage of the colon that prevents the normal passage of intestinal contents, gas, and stool. It can become life-threatening when obstruction causes bowel ischemia, necrosis, or perforation
Also called
ICD-10
Specialty
Onset
Reviewed
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OverviewOverview
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Etiology & Risk FactorsEtiology & Risk Factors
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PathophysiologyPathophysiology
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Clinical PresentationClinical Presentation
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History TakingHistory Taking
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Physical ExaminationPhysical Examination
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InvestigationsInvestigations
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DiagnosisDiagnosis
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ManagementManagement
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ComplicationsComplications
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PrognosisPrognosis
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Key Points / Clinical PearlsKey Points / Clinical Pearls
Overview
Large Bowel Obstruction is most commonly caused by:
- Colorectal cancer
- Volvulus
- Benign strictures, such as those related to diverticular disease
- Fecal impaction
The obstruction causes proximal accumulation of gas and intestinal contents, leading to bowel dilatation. If untreated, it may progress to ischemia, perforation, peritonitis, and sepsis.
Etiology & Risk Factors
Common causes of Large Bowel Obstruction include:
- Colorectal cancer
- Sigmoid volvulus
- Cecal volvulus
- Diverticular stricture
- Fecal impaction
- Benign colorectal strictures
- Inflammatory bowel disease
- Adhesions, less commonly than in small bowel obstruction
Risk Factors for Large Bowel Obstruction
- Older age
- Previous colorectal cancer
- Diverticular disease
- Chronic constipation
- Previous abdominal or colorectal surgery
- Neurological or psychiatric disorders predisposing to volvulus
Pathophysiology
Mechanical colonic blockage → accumulation of gas and fecal contents proximally → progressive colonic dilatation → increased intraluminal pressure → impaired venous and lymphatic drainage → mucosal ischemia → bowel necrosis → perforation → peritonitis and sepsis
Clinical Presentation
Symptoms
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Abdominal distension
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Colicky abdominal pain
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Constipation
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Obstipation
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Failure to pass flatus
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Nausea
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Vomiting, usually later than in small bowel obstruction
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Reduced appetite
Signs
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Marked abdominal distension
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Tympanic abdomen
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Colicky abdominal tenderness
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High-pitched or reduced bowel sounds
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Dehydration
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Visible peristalsis occasionally
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History Taking
- Onset and progression of abdominal pain
- Abdominal distension
- Constipation
- Passage of flatus
- Vomiting
- Change in bowel habits
- Rectal bleeding
- Weight loss
- Previous colorectal cancer
- Diverticular disease
- Previous abdominal surgery
Physical Examination
General Examination
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Vital signs
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Hydration status
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General appearance
Look for:
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Tachycardia
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Fever
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Hypotension
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Dehydration
System-Specific Examination
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Abdominal distension
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Tenderness
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Tympany
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Bowel sounds
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Guarding or rebound tenderness
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Rectal examination for masses or fecal impaction
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Investigations
Complete Blood Count
Useful when assessing:
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Infection
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Inflammation
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Anemia
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Possible bowel ischemia
Biochemistry / Specific Tests
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Electrolytes
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Urea and creatinine
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Serum lactate when ischemia is suspected
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C-reactive protein when clinically useful
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Blood gas in severe illness
These help assess dehydration, renal impairment, and bowel ischemia.
Imaging
Abdominal X-ray
May show:
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Dilated colon
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Haustral markings
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Obstructive pattern
CT Abdomen and Pelvis
The preferred imaging test in most adults with suspected Large Bowel Obstruction.
It helps identify:
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Site of obstruction
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Cause
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Tumor
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Volvulus
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Ischemia
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Perforation
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Proximal bowel dilatation
Special / Confirmatory Tests
Colonoscopy
May be used in selected stable patients for:
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Evaluation of suspected colorectal cancer
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Diagnosis of the cause
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Decompression of selected sigmoid volvulus
It is generally avoided when there is concern for perforation or severe peritonitis.
Diagnosis
-Diagnosis of large bowel obstruction is based on:
Abdominal distension + constipation/obstipation + colicky pain → imaging confirmation of colonic dilatation and a transition point → identify the underlying cause
CT abdomen and pelvis is generally the key diagnostic investigation.
Related Topics
Management
1. First-Line / Emergency Management
Immediate management includes:
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Urgent surgical assessment
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Nil by mouth
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IV fluid resuscitation
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Correct electrolyte abnormalities
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Analgesia and antiemetics
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Urinary catheter when necessary
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Nasogastric decompression if significant vomiting or proximal distension is present
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IV antibiotics when ischemia, perforation, or infection is suspected
2. Definitive Treatment
Treatment depends on the cause.
Colorectal Cancer
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Surgical resection when appropriate
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Endoscopic stenting in selected patients, particularly some left-sided malignant obstructions
Sigmoid Volvulus
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Endoscopic decompression if there is no ischemia or perforation
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Definitive sigmoid colectomy because recurrence is common
Cecal Volvulus
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Usually requires urgent surgery
Benign Stricture
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Endoscopic or surgical treatment depending on the cause and severity
3. Medical Treatment
Medical treatment is mainly supportive:
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IV fluids
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Electrolyte replacement
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Analgesia
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Antiemetics
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Antibiotics when infection, ischemia, or perforation is suspected
4. Surgical / Procedural Treatment
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Resection of obstructed or ischemic bowel
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Surgical treatment of volvulus
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Colostomy or other diversion when required
Complications
- Bowel ischemia
- Bowel necrosis
- Perforation
- Peritonitis
- Sepsis
- Septic shock
- Dehydration
- Electrolyte abnormalities
- Acute kidney injury
- Aspiration
- Death
Prognosis
-Prognosis depends mainly on:
- Cause of obstruction
- Duration of obstruction
- Presence of ischemia
- Perforation
- Patient age and comorbidities
- Speed of treatment
Early diagnosis and treatment generally lead to good outcomes, while ischemia and perforation significantly increase morbidity and mortality.
Key Points / Clinical Pearls
- Large Bowel Obstruction is a mechanical blockage of the colon.
- Common causes include colorectal cancer, volvulus, diverticular strictures, and fecal impaction.
- Typical symptoms are abdominal distension, colicky pain, constipation, and obstipation.
- Vomiting often occurs later than in small bowel obstruction.
- Colorectal cancer is an important cause, particularly in older adults.
- Sigmoid volvulus is an important cause of acute colonic obstruction.
- Cecal volvulus usually requires urgent surgery.
- Abdominal X-ray may show colonic dilatation.
- CT abdomen and pelvis is the key imaging investigation in most adults.
- Continuous severe pain, fever, peritonism, or raised lactate suggests ischemia or perforation.
- Initial treatment includes bowel rest, IV fluids, electrolyte correction, and urgent surgical assessment.
- Endoscopic decompression can be used for uncomplicated sigmoid volvulus.
- Catena F, De Simone B, Coccolini F, et al. Bowel Obstruction: A Narrative Review for All Physicians. World J Emerg Surg. 2019;14:20. PubMed .
- Vogel JD, Felder SI, Bhama AR, et al. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Colon Volvulus and Acute Colonic Pseudo-Obstruction. Dis Colon Rectum. 2021;64(9):1046-1057. PubMed .
- Frago R, Ramirez E, Millan M, Kreisler E, del Valle E, Biondo S. Current Management of Acute Colonic Pseudo-Obstruction (Ogilvie's Syndrome). Cir Esp. 2014;92(10):711-717. PubMed .
- National Library of Medicine (NIH). Large Bowel Obstruction . StatPearls.