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Surgical Infection & Sepsis — General Surgery

Basic General Surgery Question Bank

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Basic General Surgery Question Bank
Surgical Infection & Sepsis
General Surgery · Surgical Infection & Sepsis · medium
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Surgical Infection & Sepsis MCQs: practice questions

Sample Surgical Infection & Sepsis multiple-choice questions from General Surgery.

  1. Which laboratory marker is often used to follow the severity and response of systemic hypoperfusion?

    • A. Repair or control of the perforation
    • B. Use prophylaxis only for the indicated duration
    • C. Serum lactate
    • D. Appropriate timely perioperative antibiotic prophylaxis
    • E. Sepsis with organ dysfunction
  2. Which bacterial source is common in complicated intra-abdominal surgical infection?

    • A. Use prophylaxis only for the indicated duration
    • B. Sepsis with organ dysfunction
    • C. Repair or control of the perforation
    • D. Mixed aerobic and anaerobic flora
    • E. Urgent surgical exploration and debridement
  3. What is the first-line broad principle for antimicrobial treatment of severe sepsis?

    • A. Prompt empiric therapy appropriate for the suspected source
    • B. Serum lactate
    • C. Bacteroides fragilis
    • D. Distributive septic shock
    • E. Persistent hypotension requiring vasopressor support despite adequate volume resuscitation
  4. Which type of shock is most directly associated with severe systemic infection?

    • A. Drainage of the abscess
    • B. Biofilm formation
    • C. Prompt empiric therapy appropriate for the suspected source
    • D. Distributive septic shock
    • E. Infection causes tissue invasion or a clinically significant host response
  5. Which organism is commonly associated with postoperative wound infection?

    • A. Dirty/infected wound
    • B. Bacteroides fragilis
    • C. Atelectatic or inflammatory postoperative fever
    • D. Staphylococcus aureus
    • E. Serum lactate
  6. Why does sepsis commonly cause tissue edema?

  7. The most important principle in management of a surgically treatable intra-abdominal infection is

  8. A patient with an infected prosthetic device has persistent bacteremia despite antibiotics. Why can treatment fail?

  9. A patient with an abdominal abscess improves after drainage and antibiotics. This illustrates the importance of

  10. Which postoperative complication can mimic infection but lacks a bacterial source?

  11. A surgical wound becomes erythematous, tender, and purulent several days after surgery. The most likely diagnosis is

  12. Which clinical finding suggests an abscess rather than simple cellulitis?

  13. Which inflammatory mediator is strongly involved in fever and systemic inflammatory responses?

  14. What is the major physiologic consequence of severe sepsis?

  15. Which type of wound has the highest baseline contamination burden?

  16. Which mechanism allows bacteria to adhere to implanted surgical material?

  17. A postoperative patient has fever, tachycardia, hypotension, and altered mental status from an infected abdominal collection. This represents

  18. Which clinical strategy reduces unnecessary antimicrobial exposure after surgery?

  19. Which organism is strongly associated with infected abdominal surgery and anaerobic coverage needs?

  20. Which tissue-plane finding is characteristic of necrotizing fasciitis?

  21. What is the key difference between colonization and infection?

  22. A patient develops septic shock from perforated bowel. Which additional intervention is essential beyond antibiotics?

  23. Which mediator promotes endothelial activation and systemic inflammatory signaling in sepsis?

  24. Which patient is at particularly high risk for surgical infection?

  25. Why should antimicrobial therapy be narrowed when possible?

  26. A patient with necrotizing soft-tissue infection has severe pain out of proportion to examination. The next step is

  27. A patient with a postoperative intra-abdominal abscess remains febrile despite appropriate antibiotics. What is the best next principle?

  28. Which finding is most concerning for septic shock?

  29. A patient with a fluctuant postoperative collection is treated only with antibiotics and does not improve. What is most likely missing?

  30. Which intervention reduces surgical-site infection risk before incision?

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