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Atherosclerosis & Hypertension
Cardiovascular · Atherosclerosis & Hypertension · medium
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Atherosclerosis & Hypertension MCQs: practice questions
Sample Atherosclerosis & Hypertension multiple-choice questions from Cardiovascular.
The left anterior descending coronary artery is notable in coronary atherosclerosis because it is which of the following?
- A. The vessel least commonly affected by atherosclerosis
- B. The most frequently and severely affected coronary vessel
- C. A vessel with no clinical significance in ischemic heart disease
- D. mainly supplied by collateral circulation
- E. rarely associated with myocardial infarction
Which of the following is classified as a non-modifiable risk factor for atherosclerosis?
- A. Cigarette smoking
- B. Hyperlipidemia
- C. Hypertension
- D. Diabetes mellitus
- E. Advanced age
Atherosclerosis most severely and commonly affects which vessel?
- A. The abdominal aorta
- B. The popliteal artery
- C. The carotid artery
- D. The circle of Willis
- E. The renal artery
Renal artery stenosis causes secondary hypertension primarily through which mechanism?
- A. Direct destruction of the adrenal medulla
- B. Direct destruction of the glomeruli
- C. Activation of the renin-angiotensin-aldosterone system
- D. Isolated reduction in cardiac output
- E. Direct inhibition of the sympathetic nervous system
Calcification within an atherosclerotic plaque has which general relationship to plaque stability?
- A. Calcification commonly makes plaques acutely unstable
- B. Calcification has minimal relationship to plaque mechanics
- C. Calcification mainly occurs in early fatty streaks
- D. Calcification prevents any further plaque progression largely
- E. Calcified plaques may be more mechanically stable
Statins reduce cardiovascular risk in atherosclerosis primarily through which mechanism?
Elevated C-reactive protein is used clinically as a marker of which process relevant to atherosclerosis risk?
Elevated homocysteine levels are considered a risk factor for atherosclerosis primarily through which proposed mechanism?
Hyaline arteriolosclerosis, seen in benign (long-standing) hypertension, reflects which vessel wall change?
Malignant hypertension can additionally cause which acute vessel wall change?
Hyperplastic arteriolosclerosis, associated with malignant hypertension, shows which characteristic histologic pattern?
The fatty streak differs from a mature fibrous atherosclerotic plaque in which important way?
The fibrous cap of a mature atherosclerotic plaque is primarily composed of which elements?
Chronic atherosclerotic weakening of the abdominal aortic wall predisposes to which complication?
Which lipoprotein is considered protective against atherosclerosis through reverse cholesterol transport?
Which vessel layer is primarily affected in the initial stages of atherosclerotic lesion development?
The "response-to-injury" hypothesis identifies which event as the initiating step in atherosclerosis?
The juxtaglomerular apparatus contributes to blood pressure regulation primarily through secretion of which substance?
Smoking contributes to atherosclerosis development primarily through which combination of effects?
Aspirin's protective effect in atherosclerotic cardiovascular disease relates primarily to which mechanism?
Hypertensive retinopathy findings, such as arteriolar narrowing and hemorrhages, primarily reflect which underlying process?
Chronic, poorly controlled hypertension commonly leads to which cardiac structural change?
Rupture of an atherosclerotic plaque most directly leads to which acute complication?
Malignant hypertension is generally defined by which combination of clinical features?
The fatty streak, the earliest visible lesion of atherosclerosis, is composed primarily of which cells?
Intraplaque hemorrhage within an atherosclerotic lesion can cause which acute consequence?
A "vulnerable" atherosclerotic plaque, prone to rupture, is characterized by which features?
Foam cells within atherosclerotic lesions form through which receptor-mediated process?
Essential (primary) hypertension is best characterized by which feature?
Diabetes mellitus accelerates atherosclerosis primarily through which combination of mechanisms?